Volume 15 (1999) Issue 1 - Issue 6
- S M Yan, N Finato, C Di Loreto, C A Beltrami
Nuclear size of myocardial cells in end-stage cardiomyopathies
1999 Apr;21(2):174-80
Abstract: To determine the alteration of nuclear size in myocardial cells and the relationship between nuclear size and DNA ploidy classes in normal and cardiomyopathic human hearts. - K Kayser, G Kayser
Basic aspects of and recent developments in telepathology in Europe, with specific emphasis on quality assurance
Review: 1999 Aug;21(4):319-28
Abstract: Telepathology is the diagnostic work of a pathologist from a distance and includes all specific fields of diagnostic pathology, such as frozen section services, expert consultation, cytometric and histometric measurement, and continuous education. - A Takeda, A Sakata, N Takeda
Image and DNA analysis of hypertrophic myocytes in hypertensive heart disease and hypertrophic cardiomyopathy
Comparative Study: 1999 Oct;21(5):454-7
Abstract: To investigate differences in the pathophysiology of cardiac hypertrophy between patients with hypertensive heart disease (HHD) and hypertrophic cardiomyopathy (HCM). - E Kahn, F Frouin, H Bruzzoni-Giovanelli, F Calvo, R Di Paola, G Linarès-Cruz
Confocal-multilabeling, ultrasensitive TUNEL analysis of DNA breaks in individual cells
1999 Feb;21(1):1-7
Abstract: To visualize and localize fragmented DNA strands within apoptotic cells by means of fluorescence using TdT-mediated dUTP-biotin nick end labeling (TUNEL) techniques, laser scanning confocal microscopy (CLSM) and factor analysis of biomedical image sequences (FAMIS). - P Stiegler, A Giordano
Role of pRB2/p130 in cellular growth regulation
Review: 1999 Aug;21(4):363-6
Abstract: Cellular growth control in multicellular organisms has been shown to be essential to maintaining homeostasis. The retinoblastoma family of tumor suppressor proteins, pRB, p107 and pRB2/p130, encode proteins that act as transcriptional repressors of cell cycle-regulating and -promoting genes. - H Oikawa, T Masuda, A Yashima, R Satodate
Blood-flow route from the hepatic artery and portal vein to the sinusoid in normal human liver observed by confocal laser scanning microscopy
1999 Jun;21(3):255-61
Abstract: To observe the microvasculature in normal human liver. - I Tsarfaty, W G Alvord, J H Resau, R T Altstock, R Lidereau, I Bieche, F Bertrand, J Horev, R L Klabansky, I Keydar, G F Vande Woude
Alteration of Met protooncogene product expression and prognosis in breast carcinomas
Multicenter Study: 1999 Oct;21(5):397-408
Abstract: To objectively quantify the expression and prognostic implications of the met protooncogene product (Met) in human breast cancer. - L Leoncini, M T Del Vecchio, D Spina, T Megha, S Lazzi, C Bellan, P Tosi
Cell growth and death in malignant lymphomas. A quantitative analysis
1999 Feb;21(1):70-4
Abstract: To review the value of biopathologic factors in single lymphomatous patients across the boundaries of histologic classification. - M Scarpelli, R Montironi, R Mazzucchelli, D Thompson, P H Bartels
Distinguishing cortical adrenal gland adenomas from carcinomas by their quantitative nuclear features
1999 Apr;21(2):131-8
Abstract: To explore data from a set of cases of adrenal cortical adenomas with different endocrine syndromes and carcinomas to determine whether quantitative image analysis of nuclear features might be used to separate the groups. - G Carruba, M M Webber, D Bello-Deocampo, R Amodio, M Notarbartolo, N D Deocampo, J E Trosko, L A Castagnetta
Laser scanning analysis of cell-cell communication in cultured human prostate tumor cells
1999 Feb;21(1):54-8
Abstract: To investigate gap-junctional intercellular communication (GJIC) in LNCaP and DU145 human prostate cancer cells. - D Mihailović, B Dordević, V Mihailović
Nuclear volume in type I gastric intestinal metaplasia
1999 Apr;21(2):143-4
Abstract: To retrospectively compare nuclear size of epithelial cells in type I intestinal metaplasia (IM) from various pathologic lesions of gastric mucosa. - D Chassoux, J Franchi, T T Cao, P Debey
DNA content by in situ fluorescence imaging and S-phase detection, with chromatin structure preserved
1999 Dec;21(6):489-97
Abstract: To test the feasibility of in situ DNA quantitation of adherent cells' nuclei by fluorescence imaging, preserving chromatin structure and to follow-up S phase, in relation to DNA content, in order to assess the precision of DNA measurements. - M P Zucca, P S Larson, C L Rosenberg, A de las Morenas
Lack of correlation between morphometric analysis and presence of microsatellite alterations in proliferative ductal lesions of the breast
1999 Oct;21(5):369-73
Abstract: To apply morphometric studies using an image analyzer to a previously reported group of proliferative duct lesions and to compare results to see if there was a correlation between nuclear size range and monoclonality. - G A Losa, R Graber, G Baumann, T F Nonnenmacher
Effects of steroid hormones on nuclear membrane and membrane-bound heterochromatin from breast cancer cells evaluated by fractal morphometry
1999 Oct;21(5):430-6
Abstract: To evaluate the effect of steroid hormones on the ultrastructure of nuclear heterochromatin and perinuclear membranes in human MCF-7 breast cancer cells. - B Nadjari, H Motherby, T Pooschke, S Pooschke, H E Gabbert, D Simon, H D Röher, J Feldkamp, L Tharandt, A Böcking
DNA aneuploidy as a specific marker of neoplastic cells in FNAB of the thyroid
1999 Dec;21(6):481-8
Abstract: To investigate whether DNA image cytometry (ICM) could be of value in the specific identification of neoplastic cells in cytologic specimens of the thyroid. - E Ozer, S Ozkal, S Karademir, O Sağol, S Sökmen, A Coker, A Küpelioğlu, I Astarcioğlu
Angiogenesis and p53 and H-ras mutations in pancreatic ductal adenocarcinoma
1999 Dec;21(6):473-6
Abstract: To evaluate the correlation of angiogenesis and p53 and H-ras mutations with prognostic factors and proliferative activity assessed with Ki-67 protein expression by studying archival tissues from 24 patients with primary pancreatic ductal adenocarcinoma. - Q Zhu, G L Tipoe, F H White
Proliferative activity as detected by immunostaining with Ki-67 and proliferating cell nuclear antigen in benign and malignant epithelial lesions of the human parotid gland
1999 Aug;21(4):336-42
Abstract: A retrospective immunohistochemical study of parotid gland lesions was designed to evaluate the diagnostic and prognostic value of the proliferating cell nuclear antigen (PCNA) and Ki-67 with monoclonal antibodies PC 10 and MIB-1, respectively. - X Zhang, W Wu, H Lu, G Lu, L Zuo
Cellular DNA, ras p21 and p53 expression in the carcinogenesis of adenomatous colorectal polyps
1999 Oct;21(5):449-53
Abstract: To explore the possible roles of cellular DNA, oncogene ras and tumor suppressor gene p53 in the carcinogenesis of colorectal adenomatous polyps (CAP). - V Mahovlić, S Audy-Jurković, A Ovanin-Rakić, M Bilusić, M Veldić, D Babić, J Bozikov, Z Danilović
Digital image analysis of silver-stained nucleolar organizer region--associated proteins in endometrial cytologic samples
1999 Feb;21(1):47-53
Abstract: Digital image analysis was applied to determine the number, area and size of silver-stained nucleolar organizer regions (AgNORs) in cytologic samples from curettage in normal, hyperplastic and malignant endometrium. - M Scarpelli, R Belardinelli, D Tulli, L Provinciali
Quantitative analysis of changes occurring in muscle vastus lateralis in patients with heart failure after low-intensity training
Clinical Trial: 1999 Oct;21(5):374-80
Abstract: To quantitate the changes occurring in muscle vastus lateralis after exercise training of low intensity adopted for the rehabilitation of patients with chronic heart failure. - O Demirkaya, R M Cothren, D G Vince, J F Cornhill
Automated identification of stained cells in tissue sections using digital image analysis
Comparative Study: 1999 Apr;21(2):93-102
Abstract: To develop a novel automated image analysis system to differentiate immunohistochemically stained cells from background. - K Miyamoto, Z Yu, Y Z Li, A Kosaku, T Fujiwara
Effects of total parenteral nutrition on rat bile canaliculi: a stereologic analysis
1999 Dec;21(6):512-6
Abstract: To quantitate, in a stereologic manner, changes in bile canalicular morphology before and after choleretic infusion of total parenteral nutrition (TPN) and to determine whether TPN produces changes in localized regions within the hepatic lobule. - V D da Silva, R Montironi, D Thompson, H G Bartels, L Vaught, P W Hamilton, P H Bartels
Chromatin texture in high grade prostatic intraepithelial neoplasia and early invasive carcinoma
1999 Apr;21(2):113-20
Abstract: To evaluate individual nuclei from high grade prostatic intraepithelial neoplasia (PIN) lesions with early invasive carcinoma foci in the area of microinvasion and in the gland in which the microinvasion originated. - S Arai, T Nakamura, T Kimura, H Abé
Dynamic morphology of the cardiac ventricle
1999 Aug;21(4):343-6
Abstract: To describe the outline of the ventricular wall on the basis of physiologic data. - S C Liu, Y Hu, E R Sauter, M L Clapper, S Y Chen, H E Lanfranchi, P F Engstrom, A J Klein-Szanto
Image analysis of p53 and cyclin D1 expression in premalignant lesions of the oral mucosa
1999 Apr;21(2):166-73
Abstract: The expression of p53 and cyclin D1 proteins was analyzed by image analysis in oral premalignant lesions and normal oral mucosa. - A Sampedro, A Salas-Bustamante, M López-Artimez, J L García-Muñíz, G Urdiales
Cell cycle flow cytometric analysis in the diagnosis and management of colorectal carcinoma
Clinical Trial: 1999 Aug;21(4):347-52
Abstract: To establish prognostic models and protocols for individualized management in colorectal carcinoma patients based on both clinical and DNA flow cytometric parameters. - R A Shaw, F B Guijon, M Paraskevas, S L Ying, H H Mantsch
Infrared spectroscopy of exfoliated cervical cell specimens. Proceed with caution
1999 Aug;21(4):292-302
Abstract: To determine whether diagnostic information may be recovered from the infrared spectra of exfoliated cell specimens by using a novel spectral feature extraction method, in conjunction with linear and quadratic discriminant analysis, for spectral classification. - M Ziol, M C Vacher-Lavenu, D Heudes, J Ferrand, V Mayelo, V Molinié, S Slama, C Marsan
Expert consultation for cervical carcinoma smears. Reliability of selected-field videomicroscopy
1999 Feb;21(1):35-41
Abstract: To evaluate the diagnostic accuracy of videomicroscopy image selection for expert consultation in cervical cytology. - L Si, H Si, Y Chen, Y Sun, Y Wing
B7-1 antigen expression in tumor cells from cancerous human tissues
1999 Dec;21(6):521-6
Abstract: To explore the expression of B7-1 antigen (Ag), the most important costimulatory molecule for T-lymphocyte activation, on tumor cells from cancerous human tissues. - P W Hamilton, P H Bartels, N Anderson, D Thompson, R Montironi, J M Sloan
Case-based prediction of survival in colorectal cancer patients
1999 Aug;21(4):283-91
Abstract: To develop an approach to the prediction of survival in patients with colorectal cancer using nearest neighbor analysis and case-based reasoning. - P Ballanti, A Zullo, V Rinaldi, C Hassan, V De Francesco, M Giustini, F Taggi
Measurement variability and diagnostic sensitivity of gastric mucosal inflammatory cell morphometry
1999 Feb;21(1):21-8
Abstract: To assess the variability and sensitivity of morphometric measures of gastric mucosal lymphocyte and plasma cells to determine a systematic procedure for evaluating the density of these mononuclear inflammatory cells (MNC). - N Dioguardi, F Grizzi, P Bossi, M Roncalli
Fractal and spectral dimension analysis of liver fibrosis in needle biopsy specimens
Clinical Trial: 1999 Jun;21(3):262-6
Abstract: To evaluate the usefulness of a reliable and reproducible mathematical scoring system based on fractal geometry for quantifying the irregular pattern in fibrosis commonly seen in liver biopsy specimens from chronic liver diseases. - O Sasaki, K Soejima, D Korenaga, Y Haraguchi
Comparison of the intratumor DNA ploidy distribution pattern between differentiated and undifferentiated gastric carcinoma
Comparative Study: 1999 Apr;21(2):161-5
Abstract: To compare the differences in intratumor DNA ploidy distribution pattern between differentiated and undifferentiated carcinoma of the stomach. - R Pomante, A Santinelli, G Muzzonigro, R Montironi
Nodular hyperplasia of the prostate. Quantitative evaluation of secretory cell changes after treatment with finasteride
1999 Feb;21(1):63-9
Abstract: To quantitatively evaluate the changes in the secretory cells in nodular hyperplasia of the prostate after treatment with finasteride. - C C Solomides, R Zimmerman, M Bibbo
Semiquantitative assessment of c-erbB-2 (HER-2) status in cytology specimens and tissue sections from breast carcinoma
Comparative Study: 1999 Apr;21(2):121-5
Abstract: To determine whether various methods of fixation of surgical pathology specimens from breast carcinomas would influence the outcome of evaluation of the expression levels of c-erbB-2 (HER-2). For this, comparisons were made between (1) alcohol-fixed (95%) and air-dried smears from fresh surgical pathology specimens of breast carcinomas, and (2) formalin-fixed, paraffin-embedded tissue sections of the same specimens. - K P de Jong, M Brinker, M van Veen, T Daemen, G L Scherphof, M J Slooff
[3H] thymidine incorporation into whole liver as an alternative to [3H] thymidine incorporation into DNA as a parameter of cell proliferation in regenerating liver tissue in rats
1999 Dec;21(6):498-504
Abstract: To monitor liver regeneration following partial hepatectomy, liver cell proliferation can be measured by assaying in vivo [3H]thymidine incorporation into liver cell DNA. We hypothesized that [3H] thymidine incorporation into whole liver tissue parallels [3H] thymidine incorporation into liver cell DNA, both in high proliferating and low proliferating liver. - M C Gorisse, L Venteo, M Pluot
A method for simultaneous quantification of monoclonal antibody Ki-67 and DNA content by flow cytometry. Application to breast carcinomas
1999 Feb;21(1):8-16
Abstract: To seek a method assessing Ki-67 immunostaining and DNA content by flow cytometry simultaneously. - K Miyakawa, Y Y Myint, K Takahashi
Effects of recombinant human macrophage colony-stimulating factor on proliferation, differentiation and survival of Kupffer cells in the liver of adult mice
1999 Aug;21(4):329-35
Abstract: To investigate the effects of macrophage colony-stimulating factor (M-CSF) on the proliferation, differentiation and survival of Kupffer cells in the liver of adult mice. - A Carbone, F G Serra, A Rinelli, D Terribile, M Valentini, R Bellantone, S Rossi, G Ausili-Cèfaro, L Nardone, M Piantelli, A Capelli, F O Ranelletti
Morphometric prognostic index in breast cancer
Clinical Trial: 1999 Jun;21(3):250-4
Abstract: To assess the ability of the morphometric prognostic index (MPI) in predicting clinical outcome in a group of breast cancer patients with short-term follow-up and to assess the relationship between MPI and other prognosticators. - Y Collan
The Ebbeson-Tang formula. Theoretical background of an alternative to the disector in stereologic cell count studies
1999 Apr;21(2):147-50
Abstract: To evaluate the formula of Ebbeson and Tang (FET) with respect to the disector (DS) principle. - P Karakitsos, B Cochand-Priollet, A Pouliakis, P J Guillausseau, A Ioakim-Liossi
Learning vector quantizer in the investigation of thyroid lesions
Comparative Study: 1999 Jun;21(3):201-8
Abstract: To investigate the capability of the learning vector quantizer (LVQ) in the discrimination of benign from malignant thyroid lesions. - P Querzoli, G Albonico, S Ferretti, R Rinaldi, E Magri, I Nenci
Quantitative immunoprofiles of breast cancer performed by image analysis
Comparative Study: 1999 Apr;21(2):151-60
Abstract: To determine the biopathologic profiles of breast cancer for greater knowledge of tumor natural history and clinical outcome. - B Nadjari, A Kersten, B Ross, H Motherby, R Krallmann, R Sundmacher, A Böcking
Cytologic and DNA cytometric diagnosis and therapy monitoring of squamous cell carcinoma in situ and malignant melanoma of the cornea and conjunctiva
1999 Oct;21(5):387-96
Abstract: To investigate the diagnostic accuracy of exfoliative cytology of the cornea and conjunctiva and DNA image cytometry for quality control and monitoring of therapy for malignant neoplasms. - R A Williams, J P Baak, G A Meijer, I G Charlton
Influence of section thickness, mean nuclear diameter and nuclear crowding on DNA ploidy in histologic sections of melanocytic skin lesions
1999 Oct;21(5):413-24
Abstract: To determine the influence of section thickness, nuclear diameter (MND) and area percentage of nuclei (a measure of nuclear crowding) on histologic DNA ploidy assessed by image cytometry (ICM) of primary melanocytic skin neoplasms (MSNs). - R Martín, N Sneige, M Vásquez, M Aragón-Flores, G Martín, C Marrón, L Santamaría
Stereologic estimates of volume-weighted mean nuclear volume in aspiration smears of ductal breast carcinoma. Correlation with cytologic grade, tumor size and lymph node status
1999 Jun;21(3):185-93
Abstract: To estimate cytologic volume-weighted mean nuclear volume and correlate it with other prognostic factors, such as tumor diameter and cytologic grading in relation to nodal infiltration. - L A Castagnetta, A Traina, M Liquori, L Marasà, R Amodio, M Di Falco, M Miele, L Rausa, G Carruba
Quantitative image analysis of estrogen and progesterone receptors as a prognostic tool for selecting breast cancer patients for therapy
1999 Feb;21(1):59-62
Abstract: To assess estrogen and progesterone receptor presence in human breast tumors using immunocytochemical analysis. - C Hewitt, M Tarnoff, M Goodman, R Ramsamooj, V Chin, E J Doolin
Use of three-dimensional microscopy with multiple oblique illumination in evaluating cytopathology preparations
Comparative Study: 1999 Apr;21(2):139-42
Abstract: To analyze whether the use of multiple oblique illumination (MOI), in contrast to axial illumination (AI), improves imagery in bright field microscopy. Specimens containing thick cell clusters, such as cervical Pap smears, are often misread because of out-of-focus cell clusters. We hypothesized that visualization of these specimens with MOI would enhance this information as compared with AI. - M Kai, O Nunobiki, E Taniguchi, Y Sakamoto, K Kakudo
Quantitative and qualitative analysis of stain color using RGB computer color specification
1999 Dec;21(6):477-80
Abstract: To establish standardized Papanicolaou stain for cytology using RGB color specification. This new method was formerly used in DTP software application for computer color specification. - Y Collan, J Haikonen, C Sundfors
Fraction of neoplastic cells in breast cancer samples. Correction for the oncogene amplification test
1999 Jun;21(3):235-9
Abstract: To develop the necessary correction for the polymerase chain reaction-based oncogene amplification test applied to paraffin-embedded tissue sections. - L Matturri, B Colombo, A M Lavezzi
Evidence for apoptosis in non-small cell lung carcinoma. Relationship with cell kinetics and prognosis
1999 Jun;21(3):240-4
Abstract: To investigate cell death via apoptosis in non-small cell lung carcinoma (NSCLC) and its correlation with proliferative indices and follow-up. - H Luo, P Zhu, R Xu, J Cheng, X Zhao, J D Wang
Inhibition of DNA synthesis in isolated human endometrial cells by a levonorgestrel-releasing intrauterine device
1999 Oct;21(5):409-12
Abstract: To estimate the effect of an intrauterine device (IUD) releasing 20 micrograms levonorgestrel (LNG) per 24 hours on DNA synthesis in human endometrial cells before and after 12 months of use. - T Sawai, K Goto, M Watanabe, W Endoh, K Ogata, H Nagura
Constructing a local district telepathology network in Japan. Diagnosis of intraoperative frozen sections via telepathology over an integrated service digital network and the National Television Standard Committee System
Multicenter Study: 1999 Feb;21(1):81-4
Abstract: To construct a local telepathology network between the Department of Pathology, Tohoku University Hospital, and Koritu Kesennuma Hospital, about 150 km away. - H Uzuki, T Watanabe, Y Katsura, T Sawai
Quantitative histochemical study of hyaluronic acid binding protein and the activity of uridine diphosphoglucose dehydrogenase in the synovium of patients with rheumatoid arthritis
1999 Feb;21(1):75-80
Abstract: To examine hyaluronic acid (HA) dynamics in synovia with rheumatoid arthritis (RA), relying on a new quantitative technique introduced into histochemistry. - F Mangili, C Cigala, G Santambrogio
Staining apoptosis in paraffin sections. Advantages and limits
1999 Jun;21(3):273-6
Abstract: To describe the advantages and limits of apoptosis detection on paraffin sections by TdT-mediated dUTP nick end labeling (TUNEL). - G R Ogden, A J Wight, J G Cowpe
Quantitative oral exfoliative cytology. Effect of alcohol on normal buccal mucosa
1999 Apr;21(2):126-30
Abstract: To assess the effect of chronic alcohol intake on the DNA distribution and cell area of normal oral mucosal cells. - C Bertoni-Freddari, L Galeazzi, T Casoli, P Fattoretti, U Caselli, R Paoloni
Quantitation of intraplatelet Ca++ deposits as a potential marker of senility
1999 Dec;21(6):517-20
Abstract: To perform a morphometric evaluation of calcium deposits in human platelets as a quantitative procedure to seek a potential marker of senility in a peripheral cellular model. - R A Williams, J P Baak, G A Meijer, I G Charlton
DNA ploidy and nuclear morphometry for the classification of dysplastic nevi
Comparative Study: 1999 Oct;21(5):437-44
Abstract: To examine the diagnostic value of DNA ploidy and nuclear morphometric features in sporadic dysplastic nevi as compared to those in compound nevi and melanoma. - J A Freed
Improved correction of quantitative nuclear DNA (ploidy) measurements in tissue sections
Comparative Study: 1999 Apr;21(2):103-12
Abstract: To evaluate, using a computer model, the advantages for ploidy measurements of selecting only center-containing sections of nuclei in ultrathin, very thick or relatively thick tissue sections. - J F Casanova, A Torres, F Martínez-García, D Hardisson, M Nistal, J Regadera
Statistical considerations in the methodology of quantifying immunocompetent cells in tumors
Comparative Study: 1999 Jun;21(3):227-34
Abstract: To quantify immunocompetent cell (IC) density for different testicular tumors and antibodies and to verify if the results of the comparisons depend on the antibody used. - C Boudry, P Herlin, M Coster, J L Chermant
Influence of sample size on image cytometry of DNA ploidy measurements
1999 Jun;21(3):209-15
Abstract: To assess the number of nuclei required for significant image cytometry DNA ploidy measurements on one archival case of breast cancer. - G O Elpek, T Gelen, F Güleç, M Sedele, T Karpuzoğlu, I Süleymanlar
Stereologic estimation of mean nuclear volume in well-differentiated adenocarcinomas and carcinoma in situ of the gallbladder
1999 Oct;21(5):445-8
Abstract: To investigate mean nuclear volume of cells in well-differentiated adenocarcinomas (20 cases) and carcinoma in situ (20 cases) of the gallbladder by the principle of estimation of the volume of particles with arbitrary shapes. - H Yamanami, R Chiba, M Kobari, S Matsuno, T Takahashi
Total number and size distribution of hepatic metastases of carcinoma
1999 Jun;21(3):216-26
Abstract: To quantify the susceptibility of carcinoma to hepatic metastases by studying autopsy livers with carcinoma metastases, the primary sites of which were mostly the digestive organs. - M Nacher, S Serrano, M L Mariñoso, J Lloreta, L Aguilar, E Lerma, A Díez, J Aubia
DNA image cytometry. An alternative method in osteoblast proliferation assays
Comparative Study: 1999 Oct;21(5):381-6
Abstract: To assess whether DNA image cytometry can be used as an alternative method to tritiated thymidine uptake quantification in osteoblast proliferation assays. STUD DESIGN: Proliferation of normal human osteoblasts incubated with normal human serum at 0%, 2.5%, 5%, 10%, 20% and 40% was quantified by tritiated thymidine uptake quantification and DNA image cytometry. - Z Mijović, C Kutlesić, D Mihailović, D Stojanović, G Penev, B Djordjević
Roundness of epithelial nuclei in bronchial mucosa
1999 Oct;21(5):458-60
Abstract: To estimate the shape of epithelial nuclei in bronchial mucosa. - E Ozer, O Sağol, F Kuyucuoğlu
Ki-67 immunostaining and stereologic estimation of nuclear volume in melanocytic skin tumors
1999 Feb;21(1):42-6
Abstract: To investigate the proliferative activity and mean nuclear volume (MNV) of melanocytic skin tumors. - C Zannini, S Turchetti, R Guarch, D Buffa, C Pesce
Cell counting and three-dimensional reconstruction to identify a cellular wave in human spermatogenesis
1999 Aug;21(4):358-62
Abstract: To collect quantitative and stereologic data on the main cell types represented in the seminiferous tubule in order to produce a three-dimensional representation of the morphologic events of normal cell production and maturation. - H Miao, K Han, F Gu
Stereologic estimates of glomerular volume in unilaterally nephrectomized rats
1999 Feb;21(1):89-92
Abstract: To quantitatively evaluate the changes in glomeruli in unilaterally nephrectomized adult rats by unbiased stereologic techniques. - A Sakata, S Takasaki, M Kawakami
Three-dimensional image analysis of the hepatic restructuring process in chronic active hepatitis
1999 Jun;21(3):185-93
Abstract: To elucidate the process of hepatic restructuring in the course of chronic hepatitis from a morphologic viewpoint. - O Sasaki, K Kido, S Nagahama
DNA ploidy, Ki-67 and p53 as indicators of lymph node metastasis in early gastric carcinoma
1999 Feb;21(1):47-53
Abstract: To perform flow cytometric and immunohistochemical analysis of early gastric carcinoma in order to investigate the clinical value of DNA ploidy, Ki-67 and p53 as indicators of lymph node metastasis. - P Dey, U K Luthra, A Prasad, Z A Sheikh, S S George
Cytologic grading and DNA image cytometry of breast carcinoma on fine needle aspiration cytology smears
1999 Feb;21(1):17-20
Abstract: To correlate the cytologic grade of breast carcinoma with DNA image cytometry (ICM) and nuclear area on fine needle aspiration cytology (FNAC) smears. - V K Iyer, K Kapila, S Agarwala, A K Dinda, K Verma
Wilms' tumor. Role of fine needle aspiration and DNA ploidy by image analysis in prognostication
Comparative Study: 1999 Dec;21(6):505-11
Abstract: To evaluate the utility of cytomorphologic features and DNA ploidy estimation in fine needle aspirates (FNAs), from Wilms' tumors for prognostication. - D Miliaras
Volume-corrected mitotic index and p53 immunoreactivity in borderline and malignant epithelial ovarian tumors
Comparative Study: 1999 Oct;21(5):425-9
Abstract: To determine if there are differences in p53 immunoreactivity and proliferation rate using the volume-corrected mitotic (M/V) index between borderline and malignant ovarian tumors. - E M Wojcik, T J Bassler Jr, R Orozco
DNA ploidy in seminal vesicle cells. A potential diagnostic pitfall in urine cytology
1999 Feb;21(1):29-34
Abstract: To verify that abnormal DNA ploidy in urine cytology can occasionally be attributed to contamination by seminal vesicle cells. - A M Rijken, J A Belien, T M van Gulik, M M Polak, G J Offerhaus, D J Gouma, J P Baak
DNA quantitation of distal bile duct carcinoma measured by image and flow cytometry
Comparative Study: 1999 Aug;21(4):303-10
Abstract: To evaluate discrepancies between flow cytometry (FCM) and image cytometry (ICM), ploidy incidence and relation between DNA ploidies and survival in distal bile duct carcinomas (DBDCs). - K Veropoulos, G Learmonth, C Campbell, B Knight, J Simpson
Automated identification of tubercle bacilli in sputum. A preliminary investigation
1999 Aug;21(4):277-82
Abstract: To use an automated method to detect tubercle bacilli in sputum specimens. - M Neuburger, Y Xia, G W Herget, Y Huang, C P Adler
Prognostic significance of DNA image cytophotometry for osteosarcoma
1999 Dec;21(6):461-7
Abstract: To investigate the prognostic significance of DNA image cytophotometric data. - T Mairinger, R Happacher, C Gabl, Y Hoffmann, D Ofner, K W Schmid, A Gschwendtner
Mean weighted nuclear volumes in colonic adenocarcinomas. Evaluation of prognostic significance
1999 Jun;21(3):194-200
Abstract: To investigate the correlation of stereologically estimated mean weighted nuclear volumes of tumor cell nuclei (MWNV) with other prognostic factors and survival in colonic adenocarcinomas. - K P Riesener, L Füzesi, S Biesterfeld, A Götzen, R Kasperk, V Schumpelick
Prognostic value of DNA image cytometry in resected colorectal hepatic metastases
1999 Aug;21(4):311-8
Abstract: To determine the role of DNA image cytometry (DNA ICM) as a useful predictor of outcome following the resection of colorectal hepatic metastases. - J Slodkowska, J Sikora, W Androsiuk, P Rudziński, A Radomyski
Lung carcinoids. Tumor angiogenesis in relation to clinicopathologic characteristics
1999 Jun;21(3):267-72
Abstract: To evaluate the prognostic value of carcinoid angiogenesis for the presence of lymph node metastases, histologic subtype and tumor size. - J Azúa, P Romeo, M Morales, T Castiella, J Azúa Jr
DNA quantification as a prognostic factor in colorectal adenocarcinoma
1999 Dec;21(6):468-72
Abstract: To determine if DNA quantification, studied in cytologic samples obtained by fiberendoscopy, has predictive value in colorectal adenocarcinoma. - A Sakata, A Takeda, S Takasaki
Three-dimensional image analysis of hepatic restructuring in liver cirrhosis
1999 Apr;21(2):181-4
Abstract: To investigate the three-dimensional structure, including the angioarchitecture, of the cirrhotic liver and clarify morphogenesis of the cirrhotic nodule.